Radioisotope transfer with pharmaceutical-grade sealing, integrated ionization measurement and bubble point test.
Activity from the cyclotron has to reach the right synthesis cell. The CVRP II connects six or eight target lines to the cells downstream and leaves the routing to you.
It works with the cyclotron, the cells and the modules you already have. Valves in PEEK or steel, rated to 100 bar.
In a transfer system, residual activity and deposits can accumulate along the path, shortening the service life of valves and lines.
In the CVRP II a washing system circulates sterile water for injection through the entire path, before and after each production run.
The recovered water is available for microbiological sampling, so the microbial load of the lines is monitored without consuming enriched water.
The incoming activity of each target line is measured in an ionization chamber before it reaches the synthesis module.
This makes it possible to determine the production yield of the cyclotron in use, and supports the planning of maintenance intervals.
High-purity helium is bubbled through the solution held in the mother vial before dispensing, passing through a 0.22 µm sterilizing filter, so that the activity is homogeneous across the dispensed doses.
EU GMP Annex 1 and the European Pharmacopoeia require the integrity of the sterilizing filter to be verified.
The CVRP II performs the bubble point test at the end of dispensing, directly in the dispensing cell. The test runs manually or automatically, with pressure rising from 0 to 7 bar.
The CVRP II is configured to match your requirements and adaptable to custom equipment. Please contact us to design your CVRP II system.
Send us your requirements and we will respond directly with specifications and part numbers.